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Berlin Radio Interview on the ‘Neurobiology of Artficial Intelligence’ (in German)

Berlin Radio Interview on the ‘Neurobiology of Artficial Intelligence’ (in German)

July 16, 2025

Berlin Radio (RBB) interview about the research in the Hiesinger lab and its connection to understanding information encoding in biological and artificial neural networks – the topic of The Self-Assembling Brain. The interview ‘Die Neurobiologie der Künstlichen Intelligenz’ (in German) is available here. A related online lecture ‘Neurobiology of Artificial Intelligence’ (recorded by IEEE Computational Intellgence Society, Dec. 2024, in…

Hiesinger Lab Grant Award: The Information Content of Brain Wiring

July 2, 2025

The information content of the brain, i.e. the size of a hard drive it would take for lossless up- anddownloading of information stored in biological neural networks of any size, is unknown. Bycontrast, the information content of artificial neural networks that underlie virtually allcontemporary artificial intelligence, is well defined and can be saved on a hard drive in a precisenumber…

On Neuromorphic Computing

July 2, 2025

There is an exciting, increasing interest of the neuromorphic computing community in the development of biological neural networks and The Self-Assembling Brain. Recent invited lectures include the International Conference for Neuromorphic Computing and Engineering (Aachen, 2024), and the International Workshop on Reliable and Systainable Neuromorphic Hardware (York, 2025), with production of a mindmap during the introductory keynote: Next opportunity to…

From the author’s lab: New research paper on self-organization of brain wiring in the journal Science

May 5, 2024

Axonal self-sorting without target guidance in Drosophila visual map formation Agi et al., 2024, Science. PMID: 38452066, DOI: 10.1126/science.adk3043 Abstract The idea of guidance toward a target is central to axon pathfinding and brain wiring in general. In this work, we show how several thousand axonal growth cones self-pattern without target-dependent guidance during neural superposition wiring in Drosophila. Ablation of…

Book Review in Mathemafrica

April 16, 2023

originally published here by Jonathan Shock on April 9, 2023 Science so often lives in silos, or perhaps more accurately silos of Babel. We sit in our offices, ignoring a great deal of what is happening down the corridor from us, let alone in the building next door or the one on the other side of the campus.  A lot…

New Biography of Mike Gaze

March 27, 2023

Michael Gaze (1927-2012) was a contemporary of Roger Sperry who went in search of the rules of brain wiring. Inspired by Sperry, Gaze tested the core ideas of the field using electrophysiology to map connectivity – and described just how relative positioning, as opposed to Sperry’s rigid code, can lead to synaptic specificity in the visual system. Never as famous…

The Self-Assembling Brain Audiobook is coming!

March 27, 2023

Since Princeton University Press has announced the release of the Paperback of The Self-Assembling Brain for Dec. 13, 2022, we are glad to announce that the audio rights have been licensed to Recorded Books! This is going to be interesting, especially for the 10 dialogues of our favorite geneticist, robotics engineer, Artificial Intelligence Researcher and Neuroscientist. We’ll post the release…